Author

Tomohito Nagaoka

Aomori Public UniversityORCID 0000-0001-8802-9593Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:DNA methylation· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Daisuke WakuiD· 3 shared Hiroki OotaiD· 3 shared Kae KoganebuchiiD· 3 shared Minoru YonedaiD· 3 shared Ryuzaburo Takahashi· 3 shared Yoshiki Wakiyama· 3 shared Akio Tanino· 2 shared Guido ValverdeiD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Daisuke WakuORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cold adaptation in Upper Paleolithic hunter-gatherers of eastern Eurasia

Yusuke Watanabe, Yoshiki Wakiyama, Daisuke Waku, Guido Valverde, Akio Tanino, Mizuki HAYASHI, Izumi Naka, Yuka Nakamura, Tsubasa Suzuki, Kae Koganebuchi, Takashi Gakuhari, Takafumi Katsumura, Masami Ogawa, Atsushi Toyoda, Pornlada Nuchnoi, , Hiroki Oota

This study analyzes 42 genomes from Jomon hunter-gatherers to show they adapted to cold environments through positive selection during the Last Glacial Maximum.

Science Advances · Aug 12, 2026Peer-reviewedEvolutionary Biology

Endemic demographics of the Jomon people estimated based on complete mitogenomes reveal their regional diversity

Koki Yoshida, Yoshiki Wakiyama, Guido Valverde, Akio Tanino, Daisuke Waku, Takafumi Katsumura, Motoyuki Ogawa, Tomohito Nagaoka, Kazuaki Hirata, Kae Koganebuchi, Yusuke Watanabe, Jun Ohashi, Minoru Yoneda, Ryuzaburo Takahashi, Hiroki Oota

The paper estimates the demographic history of the Jomon people using complete mitogenomes, revealing an effective population size increase during the Incipient-Initial phase not seen in present-day Japanese populations.

bioRxiv · May 16, 2024 · PreprintGenomics

Collagen of ancient bones gives an indication of endogenous DNA preservation based on the next generation sequencing technology

Yuka Nakamura, Daisuke Waku, Yoshiki Wakiyama, Yusuke Watanabe, Kae Koganebuchi, Tomohito Nagaoka, Kazuaki Hirata, Jun Ohashi, Ryuzaburo Takahashi, Minoru Yoneda, Hiroki Oota

The paper uses next-generation sequencing to assess endogenous DNA preservation in ancient bones by correlating collagen residual ratios with mapping ratios in Jomon remains.

Anthropological Science · Jan 1, 2024Peer-reviewedGenomics