Kae Koganebuchi

An iPSC-based experimental framework for investigating phenotypic variation associated with Jomon ancestry in the present-day Japanese population

The paper develops a hiPSC-based framework to study ancestry-related phenotypic variation in the Japanese population, finding no hepatic triglyceride differences despite genetic associations.

Cold adaptation in Upper Paleolithic hunter-gatherers of eastern Eurasia

This study analyzes 42 genomes from Jomon hunter-gatherers to show they adapted to cold environments through positive selection during the Last Glacial Maximum.

Ancient Ryukyu Jomon contributed to past and current genetic structure of Japanese populations

This study sequenced ancient and modern genomes from the Ryukyu Archipelago to show genetic differentiation between Ryukyu Jomon and Hondo populations, with admixture occurring around 1,000 YBP.

Endemic demographics of the Jomon people estimated based on complete mitogenomes reveal their regional diversity

The paper estimates the demographic history of the Jomon people using complete mitogenomes, revealing an effective population size increase during the Incipient-Initial phase not seen in present-day Japanese populations.

Collagen of ancient bones gives an indication of endogenous DNA preservation based on the next generation sequencing technology

The paper uses next-generation sequencing to assess endogenous DNA preservation in ancient bones by correlating collagen residual ratios with mapping ratios in Jomon remains.

Jomon genome sheds light on East Asian population history

The paper analyzes the genome of a Jomon individual to infer migration patterns into East Asia, finding multiple waves and a coastal route from Southeast Asia.

A new targeted capture method using bacterial artificial chromosome (BAC) libraries as baits for sequencing relatively large genes

This paper introduces a new targeted capture method, BDC, using BAC libraries as baits for sequencing large genes, showing it is cost-effective and maintains data quality comparable to commercial kits.

Analysis of ancient human mitochondrial DNA from Verteba Cave, Ukraine: insights into the origins and expansions of the Late Neolithic-Chalcolithic Cututeni-Tripolye Culture

The paper analyzes ancient mitochondrial DNA from Verteba Cave, Ukraine, to study the genetic origins and demographic history of the Tripolye Culture, finding low mtDNA diversity and evidence of demographic expansion during peak occupation.