Author

Nanjie Deng

Pace UniversityORCID 0000-0001-8805-3526Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Avik BiswasiD· 1 shared Dmitry LyumkisiD· 1 shared Qinfang SuniD· 1 shared Ronald Levy· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBiophysics

Avik BiswasORCID

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1 paper

Recent·Most cited

BiophysicsVirusesPeer-reviewedJan 2, 2024

Elucidating the molecular determinants for binding modes of a third-generation HIV-1 integrase strand transfer inhibitor: Importance of side chain and solvent reorganization

Qinfang Sun, Avik Biswas, Dmitry Lyumkis…·Nanjie Deng

This study identifies molecular determinants of binding modes for a third-generation HIV-1 integrase inhibitor, showing that side chain and solvent reorganization, along with conformational entropy, influence ligand binding preferences in closely related viral intasomes.

6 citations

humanstructural biology

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