Avik Biswas

Using phage display for rational engineering of a higher affinity humanized 3-phosphohistidine-specific antibody

This paper describes the engineering of high-affinity 3-phosphohistidine-specific antibodies using phage display and validates their utility in detecting pHis proteins in mammalian cells.

SEASONAL PM2.5 DIFFERENTIALLY REGULATES JAK2/STAT3 SIGNALING IN RURAL AND URBAN COHORTS

This study shows seasonal PM2.5 exposure differentially affects JAK2/STAT3 signaling and oxidative stress in urban and rural cohorts, increasing lung cancer risk in urban areas.

De Novo Hydration of Cryo-EM Reconstructions through Molecular Dynamics Simulations of the Excess Chemical Potential

This paper introduces a method using molecular dynamics simulations to predict water positions in cryo-EM maps by analyzing excess chemical potential, showing high agreement with experimental data.

Evolutionary Sequence and Structural Basis for the Epistatic Origins of Drug Resistance in HIV

This study identifies the structural and sequence basis of epistatic interactions driving drug resistance in HIV by combining sequence models and molecular dynamics simulations.