Systems BiologybioRxivPreprint
Differences between in vivo and ex vivo models drive divergent perturbation outcomes
Aarathy Ravi Sundar Jose Geetha, Cynthia del Valle, Wolfgang Esser‐Skala…·Nikolaus Fortelny
The paper compares perturbation outcomes in in vivo and ex vivo hematopoietic stem cell models, finding systematic biases and challenges in predicting in vivo effects from ex vivo data.