Sidharth Chopra

This study identifies lysosomal acid lipase (LIPA) as a key enzyme regulating cholesterol metabolism during phagosomal maturation, linking lipid catabolism to antimicrobial defense.

This paper describes the development of a platinum-based antibiotic, Pt1, which shows potent antibacterial activity against resistant Staphylococcus aureus strains and demonstrates in vivo efficacy in a murine infection model.

This study identifies synergistic combinations of Vancomycin and β-lactams against drug-resistant mycobacteria, showing improved bactericidal activity and reduced bacterial load in vitro and in vivo.