Author

Abdul Akhir

Central Drug Research InstituteORCID 0000-0002-7892-4997Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Sidharth ChopraiD· 2 shared Angelo FreiiD· 1 shared Ann-Britt Schäfer· 1 shared Bhawna BhawnaiD· 1 shared Çağrı ÖzsaniD· 1 shared Deepanshi SaxenaiD· 1 shared Dhiraj KumariD· 1 shared Fredrik WesterlundiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

Sidharth ChopraORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintSep 22, 2026

Lysosomal acid lipase regulates cholesterol metabolism during phagosomal maturation

Ojal Saharan, Bhawna Bhawna, Shakuntala Surender Kumar Saraswati…·Siddhesh S. Kamat

This study identifies lysosomal acid lipase (LIPA) as a key enzyme regulating cholesterol metabolism during phagosomal maturation, linking lipid catabolism to antimicrobial defense.

DOI 10.64898/2026.09.18.752819

experimental assay

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Microbiologynpj Antimicrobials and ResistancePeer-reviewedMay 8, 2026

A Platinum Butterfly Effect: Small Changes Turn an Anticancer Drug into a Non-toxic Metalloantibiotic with In Vivo Efficacy

Çağrı Özsan, Ann-Britt Schäfer, Abdul Akhir…·Angelo Frei

This paper describes the development of a platinum-based antibiotic, Pt1, which shows potent antibacterial activity against resistant Staphylococcus aureus strains and demonstrates in vivo efficacy in a murine infection model.

1 citation

mouseexperimental assay

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