Author

Steven J. Charlton

University of NottinghamORCID 0000-0001-8841-2752Unclaimed ORCID profile · follow to get notified of new preprints

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1

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David A. SykesiD· 1 shared Hannah M.F. Comfort· 1 shared Jack M. Lochray· 1 shared Palash Jain· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperNeuroscience

David A. SykesORCID

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1 paper

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NeurosciencebioRxivPreprintNov 14, 2021

Exploring the kinetic selectivity of antipsychotics for dopamine D2 and 5-HT2A receptors: implications for the prevalence of EPS and receptor occupancy

David A. Sykes, Jack M. Lochray, Hannah M.F. Comfort…·Steven J. Charlton

This study measures the kinetic binding properties of antipsychotics at 5-HT2A and D2 receptors and correlates them with extrapyramidal side effects (EPS) at therapeutic doses.

4 citations

experimental assay

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