Jeanne E. Barthold

This study develops human-derived granular extracellular matrix hydrogels for osteochondral repair, showing distinct biochemical and mechanical properties between cartilage and bone gECM.

The paper introduces gECM hydrogel wafers as shelf-stable 2.5D substrates for microphysiological modeling, showing they support cell viability and function comparable to 3D hydrogels.

This study develops and characterizes granular ECM hydrogels for five tissues, showing they retain shape, stability, and support tissue-specific cellular activity.

A granular extracellular matrix hydrogel implanted in a goat condyle provided a robust repair, filling the defect tissue with integrated, hyaline-like cartilage at 12 months.