Stephanie Ellyse Schneider

This study develops human-derived granular extracellular matrix hydrogels for osteochondral repair, showing distinct biochemical and mechanical properties between cartilage and bone gECM.

This study shows particle-only gECM wafers match hydrogel wafers in mechanical and biological performance without needing secondary polymers.

This study investigates how Lamin A/C disruption affects nuclear mechanics, chromatin architecture, and transcription in skeletal muscle in vivo, finding that it alters chromatin organization and gene expression in mechanically stiff tissues.

The paper introduces gECM hydrogel wafers as shelf-stable 2.5D substrates for microphysiological modeling, showing they support cell viability and function comparable to 3D hydrogels.

This paper develops a two-stage femtosecond laser fabrication method for PDMS membranes with tunable permeability and mechanical resilience for organ-on-chip applications.

This study develops and characterizes granular ECM hydrogels for five tissues, showing they retain shape, stability, and support tissue-specific cellular activity.

A granular extracellular matrix hydrogel implanted in a goat condyle provided a robust repair, filling the defect tissue with integrated, hyaline-like cartilage at 12 months.

This study shows that perturbed mechanical stretch induces a premature senescent phenotype in cardiac fibroblasts through distinct pathways involving p53/p21 and p16.