Author

Senén D. Mendoza

University of California, San FranciscoORCID 0000-0001-8852-4148Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Alexis VillaniiD· 1 shared Chang YeiD· 1 shared Ehud BaniniD· 1 shared Ellay Avihu· 1 shared Esther ShmidoviD· 1 shared Hao YaniD· 1 shared Ilana Lebenthal-Loinger· 1 shared Joseph Bondy‐DenomyiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Alexis VillaniORCID

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1 paper

Recent·Most cited

MicrobiologyNature MicrobiologyPeer-reviewedSep 8, 2025

Multigenerational Proteolytic Inactivation of Restriction Upon Subtle Genomic Hypomethylation

Esther Shmidov, Alexis Villani, Senén D. Mendoza…·Ehud Banin

This study shows that Pseudomonas aeruginosa inactivates its type I R-M system via proteolysis at high temperatures, leading to prolonged genomic hypomethylation and a memory effect lasting over 60 generations.

4 citations

bacteria (other)DNA methylation

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