Lucas R. Hoffman

The paper introduces UHVDB, an updateable human virome database and toolkit, and demonstrates its utility in analyzing oral/airway samples from Cystic Fibrosis patients.

This paper identifies genes essential for Staphylococcus aureus growth in CF sputum and shows that calprotectin and cysteine limit its growth.

This study shows that thymidine starvation in bacteria increases c-di-AMP, leading to STING activation and inflammation during infection.