Raymond John Pickles

Airway Epithelial SARS-CoV-2 Infectious and Repair Responses: Relationships to Age, Sex, and Post-COVID Pulmonary Syndromes

This study examines SARS-CoV-2 infection and repair responses in human airway epithelial cells, finding prolonged and incomplete repair linked to long-COVID pulmonary symptoms.

A curated collection of transcriptome datasets to study the transcriptional response in blood and nasal samples following viral respiratory inoculation and vaccination

The paper curates a collection of transcriptome datasets from viral respiratory inoculation and vaccination studies to enable reanalysis of transcriptional responses in blood and nasal samples.

Temporal High-Resolution Atlas of Human Blood Leukocyte Composition in Response to Respiratory Virus Inoculation

The paper constructs a temporal atlas of human blood leukocyte changes after respiratory virus infection, showing shared immune responses and virus-specific kinetics.

Prolonged airway explant culture enables study of health, disease, and viral pathogenesis

This study develops methods to culture human and animal airway explants for at least 14 days, preserving tissue architecture and enabling study of health, disease, and viral infection.