Isabel K. Kim

This study develops a modeling framework for gene drives in plants that includes soil seedbanks, showing how seedbanks can slow spread but reduce genetic load and provide biosafety.

This study investigates the invasion dynamics of threshold-dependent gene drives in spatially structured populations using reaction-diffusion models and individual-based simulations, revealing complex spatial containment behaviors.

This study analyzes spatial suppression gene drive dynamics, finding that larger areas and certain life history traits increase vulnerability to chasing, while resistance mechanisms affect drive performance.

The paper simulates two Anopheles homing gene drives and finds the combined drive with X-shredder is less effective than drives using the nos promoter.

This study simulates CRISPR-based underdominance gene drives using toxin-antidote principles to assess their performance and confinability in population modification and suppression.

The paper evaluates CRISPR-based toxin-antidote gene drive systems to assess their resistance resistance and regional confinement capabilities for population modification and suppression.