Benjamin C. Haller

This study develops a modeling framework for gene drives in plants that includes soil seedbanks, showing how seedbanks can slow spread but reduce genetic load and provide biosafety.

The paper introduces e3SIM, a simulator that models epidemiological, ecological, and evolutionary processes in pathogens, demonstrating its use with SARS-CoV-2 and Mycobacterium tuberculosis.

SLiM 5 extends the simulation framework to support multiple chromosomes, enabling full-genome simulations with various chromosome types.

This study models gene drive strategies for controlling fire ants, finding that suppression drives can effectively eliminate polygyne colonies but require specialized approaches to target monogyne populations.

The paper introduces a SLiM 5 model for simulating whole-genome human evolution, including sex chromosomes and mitochondrial DNA, and demonstrates its utility through simple analyses.

The paper introduces the use of tree sequences from the forwards simulator SLiM to enable interoperability between forward-in-time and coalescent simulations.

The paper extends the stdpopsim simulation framework to include realistic selection models, enabling studies of selection's impact on genetic variation across species.

The paper uses experimental evolution to study purifying selection on P-element invasion in Drosophila simulans, finding 73% of new insertions are under purifying selection with a mean selection coefficient of -0.056.

This paper provides a guide to implementing individual-based simulations in continuous landscapes, focusing on population dynamics and ecological applications.

The paper introduces slendr, an R package for simulating spatio-temporal population genomic data, and demonstrates its features through example workflows.

The paper expands the stdpopsim species catalog and improves genome simulations by adding non-crossover recombination and species-specific annotations, making simulations more realistic for non-model organisms.