Daniel J. Wozniak

This study identifies extracellular vesicles from Pseudomonas aeruginosa-infected macrophages as drivers of cardiac dysfunction in cardiomyocytes.

This study identifies genetic adaptations in Pseudomonas aeruginosa during chronic infection that lead to hyperbiofilm phenotypes through mutations in lipopolysaccharide and type IV pili biosynthesis.

The paper assesses pre-existing immunity to Cas9 proteins in people with cystic fibrosis and finds similar antibody and T cell responses to S. aureus and S. pyogenes Cas9 compared to non-CF controls.

The paper identifies a Pseudomonas aeruginosa bacteriophage, Clew-1, that uses Psl as a receptor to disrupt biofilms and reduce bacterial burden in a mouse model.

This study identifies the Pel polysaccharide as a driver of autoaggregation in S. intermedius, linking it to biofilm formation and increased pathogenicity.