Author

Ruili Huang

National Center for Advancing Translational SciencesORCID 0000-0001-8886-8311Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew C. PattiD· 1 shared Chloe Chen· 1 shared Ewy A. MathéiD· 1 shared Fang LiuiD· 1 shared Hongmao SuniD· 1 shared Jinghua Zhao· 1 shared Kennie Cruz-Gutierrez· 1 shared Menghang XiaiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioinformatics

Andrew C. PattORCID

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2 papers

Recent·Most cited

BioinformaticsPLoS ONEPeer-reviewedJan 25, 2024

Exploring NCATS In-House Biomedical Data for Evidence-based Drug Repurposing

Fang Liu, Andrew C. Patt, Chloe Chen…·Qian Zhu

The paper explores NCATS biomedical data to identify drug repurposing candidates through chemical clustering and evidence mining.

5 citations

bulk RNA-seqstatistical model

𝕏 PostBluesky

BioinformaticsJournal of Chemical Information and ModelingPeer-reviewedJun 2, 2022

Retro Drug Design: From Target Properties to Molecular Structures

Yuhong Wang, Sam Michael, Shyh‐Ming Yang…·Hongmao Sun

This paper introduces retro drug design (RDD), an AI method to generate novel small molecule drugs with desired properties, and demonstrates its ability to produce compounds with biological activity and BBB permeability.

24 citations

deep learningdrug response / drug discovery

𝕏 PostBluesky