Author

Chloe Chen

Carnegie Mellon University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Organism:rat· 1

Frequent Co-Authors

Andrew C. PattiD· 1 shared Andrew Huang· 1 shared Avyi HilliD· 1 shared Bard ErmentroutiD· 1 shared David A. LewisiD· 1 shared David L. GlanzmaniD· 1 shared Ewy A. MathéiD· 1 shared Fang LiuiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperBioinformatics

Andrew C. PattORCID

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Author profile →

3 papers

Recent·Most cited

Scalable prediction of symmetric protein complex structures

Victor Yu, Perry Demsko, Roger Castells‐Graells, Hank Parker, Andrew Huang, Chloe Chen, Martin Huang, Varsitaa Srinivasan, Krishna Ajjarapu, Nica Tofighbakhsh, Richard Yu, Michael P. Lake, David L. Glanzman, Sarah E. Warren, Joseph B. Alzagatiti

This paper introduces Plica-1, a physics-based method for predicting large symmetric protein complex structures, achieving high accuracy and speed.

bioRxiv · Nov 14, 2025 · PreprintBioengineering

Exploring NCATS In-House Biomedical Data for Evidence-based Drug Repurposing

Fang Liu, Andrew C. Patt, Chloe Chen, Ruili Huang, Yanji Xu, Ewy A. Mathé, Qian Zhu

The paper explores NCATS biomedical data to identify drug repurposing candidates through chemical clustering and evidence mining.

PLoS ONE · Jan 25, 2024Peer-reviewedBioinformatics

Mechanisms regulating the frequency of inhibition-based gamma oscillations in primate prefrontal and parietal cortices

Guillermo González‐Burgos, Takeaki Miyamae, Nita Reddy, Sidney Dawkins, Chloe Chen, Avyi Hill, John F. Enwright, Bard Ermentrout, David A. Lewis

The paper investigates why gamma oscillations have higher frequency in primate prefrontal cortex compared to parietal cortex, finding no differences in GABAAR inhibition but suggesting stronger excitatory drive in prefrontal neurons.

bioRxiv · Apr 26, 2022 · PreprintNeuroscience