Alexander Klesen

This study uses single-cell RNA-sequencing and spatial transcriptomics to analyze the spatio-temporal dynamics of the fibrotic niche in cardiac repair after ventricular injury in adult mice, identifying key cell interactions and regulatory mechanisms.

This study compares stretch-activated channel activity in bone marrow-derived and cardiac tissue-resident macrophages, finding that Piezo1 activity is absent in the latter.

This study identifies two stretch-activated ion channels, Piezo1 and BKCa, in human atrial fibroblasts and shows their differential regulation in atrial fibrillation.