Author

Ethan D. Smith

North Carolina State UniversityORCID 0000-0001-8897-2143Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1 Genetics· 1 Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:C. elegans· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

Susan B CarpenteriD· 2 shared Tammy S. TollisoniD· 2 shared Xinxia PengiD· 2 shared Aaron R. JexiD· 1 shared Adam SaterialeiD· 1 shared Alan TraceyiD· 1 shared Alexandra IstishiniD· 1 shared Bernard J. PopeiD· 1 shared

Activity by Year

2022-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersGenetics

Susan B CarpenterORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

GeneticsJournal of VirologyPeer-reviewedDec 11, 2025

VILMIR is a trans-acting long noncoding RNA that enhances the host interferon response in human epithelial cells

K John, Ethan D. Smith, Alexandra Istishin…·Xinxia Peng

This study identifies VILMIR as a long noncoding RNA that enhances the host interferon response by interacting with transcriptional and translational regulators in human epithelial cells.

DOI 10.1128/jvi.01380-25

humanexperimental assay

𝕏 PostBluesky

Evolutionary BiologybioRxivPreprintOct 21, 2025

Gonadal Transcriptome Differences Between the Sexes in Wild Caught Southern Flounder (Paralichthys lethostigma) During a Critical Development Period

Sydney P. Harned, Jamie L. Mankiewicz, Ethan D. Smith…·John Godwin

This study identifies genes related to sex determination in southern flounder using transcriptome analysis of wild-caught juveniles with differing sex ratios.

DOI 10.1101/2025.10.21.683694

zebrafishbulk RNA-seq

𝕏 PostBluesky

ImmunologyJournal of VirologyPeer-reviewedMar 25, 2025

Human long noncoding RNA, VILMIR, is induced by major respiratory viral infections and modulates the host interferon response

Kristen John, Ian Huntress, Ethan D. Smith…·Xinxia Peng

This study identifies VILMIR, a novel lncRNA upregulated by respiratory viral infections and IFN-β, which modulates the host interferon response.

12 citations

humanbulk RNA-seq

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GenomicsGenome ResearchPeer-reviewedJan 1, 2022

Long-read assembly and comparative evidence-based reanalysis of Cryptosporidium genome sequences reveal new biological insights

Rodrigo P. Baptista, Yiran Li, Adam Sateriale…·Jessica C. Kissinger

The paper presents a new high-quality genome assembly and annotation for Cryptosporidium parvum IOWA, revealing structural and functional insights into its genome and evolutionary relationships with related species.

57 citations

C. eleganswhole-genome sequencing

𝕏 PostBluesky