Dorsal/NF-κB exhibits a dorsal-to-ventral mobility gradient in the Drosophila embryo
Hadel Al Asafen, Natalie M. Clark, Etika Goyal, Sadia Siddika Dima, Hung-Yuan Chen, Thomas L. Jacobsen, Rosangela Sozzani, Gregory T. Reeves
The paper quantifies Dorsal/NF-κB mobility and DNA binding along the dorsal-ventral axis of Drosophila embryos, revealing a gradient in DNA binding that affects gradient formation and downstream gene expression.
bioRxiv · Feb 14, 2026 · PreprintDevelopmental Biology