NeurosciencebioRxivPreprint
Differentiation of cortical brain organoids and optic nerve-like structures from retinal confluent cultures of pluripotent stem cells
Milan Fernando, Scott David Lee, Jesse Ray Wark…·Anai Gonzalez-Cordero
This paper describes a protocol to generate cortical brain organoids and optic nerve-like structures from retinal confluent cultures of pluripotent stem cells, showing transcriptional similarity to fetal cortex and functional network activity.