Author

Nicholas C. Turner

Institute of Cancer ResearchORCID 0000-0001-8937-0873Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Ben O’LearyiD· 2 shared Aleruchi Okachi· 1 shared Alicia F. C. OkinesiD· 1 shared Amelie ZiehmeiD· 1 shared Andrew Charles WotherspooniD· 1 shared Andrew WoolstoniD· 1 shared Anisha PateliD· 1 shared Anton Mikhailovich SafonoviD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersGenomics

Ben O’LearyORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 27, 2025

LOX inhibition disrupts a collagen-integrin-MYC axis as a translatable targeting strategy in invasive lobular carcinoma

Renée L. Flaherty, Flavia Hughes, George Sflomos…·Cathrin Brisken

LOX inhibition disrupts a collagen-integrin-MYC axis in ILC, halting tumor growth and metastasis with minimal toxicity, offering a new therapeutic strategy.

DOI 10.1101/2025.08.27.672618

humanbulk RNA-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintFeb 5, 2024

Tumor suppressor heterozygosity and homologous recombination deficiency mediate resistance to front-line therapy in breast cancer

Anton Mikhailovich Safonov, Antonio Marra, Chaitanya Bandlamudi…·Pedram Razavi

The paper identifies how germline and somatic mutations interact to cause resistance to CDK4/6 inhibitors in breast cancer and proposes a sequential treatment strategy using PARP inhibitors.

18 citations

humanwhole-exome sequencing

𝕏 PostBluesky

GenomicsClinical ChemistryPeer-reviewedAug 27, 2018

Ultra-sensitive mutation detection and genome-wide DNA copy number reconstruction by error corrected circulating tumour DNA sequencing

Sonia Mansukhani, Louise J. Barber, Dimitrios Kleftogiannis…·Marco Gerlinger

This paper develops an error-corrected cfDNA sequencing method for highly sensitive mutation detection and genome-wide copy number reconstruction in metastatic colorectal cancer.

55 citations

humanwhole-genome sequencing

𝕏 PostBluesky