BioengineeringMolecular TherapyPeer-reviewed
PBAE-PEG based lipid nanoparticles for lung cell-specific gene delivery
Bingxin Liu, Yamato Sajiki, Nicole Littlefield…·Yutaka Maeda
This paper develops PBAE-PEG and PBAE lipid nanoparticles for targeted mRNA delivery to lung cells, showing differential efficacy in transfecting pulmonary endothelial and epithelial cells via different routes.