Author

Madison S. Krieger

ORCID 0000-0001-8967-0841Unclaimed ORCID profile · follow to get notified of new preprints

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Madison S. Krieger1 paper

Biology Disciplines

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Systems Biology· 2

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Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

William GilpiniD· 2 shared Andrei H GheorgheiD· 1 shared Barsha PokhareliD· 1 shared David Alan ThompsoniD· 1 shared Denitsa MilanovaiD· 1 shared George M. ChurchiD· 1 shared George SugiharaiD· 1 shared Nadire R. Cochran· 1 shared

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2025-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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2 shared papersSystems Biology

William GilpinORCID

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2 papers

Recent·Most cited

Systems BiologybioRxivPreprintOct 23, 2026

Inference and validation of causal genetic interactions in aging human fibroblasts

Madison S. Krieger, Denitsa Milanova, David Alan Thompson…·George M. Church

This paper uses convergent cross mapping to infer causal genetic interactions from cross-sectional transcriptomic data of aging human fibroblasts and validates these interactions experimentally.

DOI 10.64898/2026.10.21.760791

humanbulk RNA-seq

Systems BiologybioRxivPreprintSep 28, 2025

Interpretable gene network inference with nonlinear causality

Madison S. Krieger, William Gilpin

This paper introduces RiCE, a physics-based algorithm for inferring gene networks from time series data, showing improved performance across multiple datasets and applications.

1 citation

bulk RNA-seqstatistical model