Author

William Gilpin

The University of Texas at AustinORCID 0000-0001-8666-6951Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Madison S. KriegeriD· 2 shared Andrei H GheorgheiD· 1 shared Barsha PokhareliD· 1 shared David Alan ThompsoniD· 1 shared Denitsa MilanovaiD· 1 shared George M. ChurchiD· 1 shared George SugiharaiD· 1 shared Nadire R. Cochran· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSystems Biology

Madison S. KriegerORCID

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2 papers

Recent·Most cited

Inference and validation of causal genetic interactions in aging human fibroblasts

Madison S. Krieger, Denitsa Milanova, David Alan Thompson, Nadire R. Cochran, Tongyao Wang, Barsha Pokharel, Robert P Ford, Andrei H Gheorghe, William Gilpin, Yoav Freund, George Sugihara, George M. Church

This paper uses convergent cross mapping to infer causal genetic interactions from cross-sectional transcriptomic data of aging human fibroblasts and validates these interactions experimentally.

bioRxiv · Oct 23, 2026 · PreprintSystems Biology

Interpretable gene network inference with nonlinear causality

Madison S. Krieger, William Gilpin

This paper introduces RiCE, a physics-based algorithm for inferring gene networks from time series data, showing improved performance across multiple datasets and applications.

bioRxiv · Sep 28, 2025 · PreprintSystems Biology