Single molecule dynamics of Dishevelled at the plasma membrane and Wnt pathway activation
Wenzhe Ma, Maorong Chen, Hong Kang, Zachary Steinhart, Stéphane Angers, Xi He, Marc W. Kirschner
This study uses single-molecule imaging to analyze Dvl2 dynamics and oligomerization during Wnt pathway activation, showing increased oligomerization and dwell time upon Wnt3a stimulation.
Proceedings of the National Academy of Sciences · Jun 29, 2020Peer-reviewedSystems Biology