Adam R. Ferguson

This study shows aerobic exercise reduces chronic pain duration and preserves descending control of nociception in male and female rats with traumatic brain injury.

This study shows that old mice experience long-term memory issues after stroke due to increased synapse removal by inflammatory cells, which can be mitigated by activating 7-nAchRs.

This study investigates how polytraumatic spinal cord injury (SCI) combined with spared nerve injury (SNI) exacerbates maladaptive plasticity in spinal motor systems through increased GluA1 expression and AMPAR currents.

This study compares transparency reporting in two neurotrauma journals, finding that a required rigor section improves some reporting practices but not all.

The paper identifies a plasma protein biomarker panel and predictive model for early cerebral edema worsening in TBI patients and reveals a neuronal-synaptic injury network associated with edema progression.

The paper introduces a centralized catalog of preclinical TBI models to improve reproducibility and accessibility by consolidating metadata from published studies.

The paper identifies a proteomic signature linked to vascular dysfunction and neurodegeneration in aging brains, highlighting thromboinflammation as an early pathway to tauopathy.

The paper evaluates NeuroCombat's effectiveness in harmonizing multi-site neuroimaging data from TBI rat models, showing improved statistical power and effect size after outlier removal and global sham population harmonization.

The paper describes best practices for western blot experiments and introduces blotRig, a tool to improve rigor and reproducibility in quantitative analysis.

The paper identifies plasma proteomic signatures associated with CADASIL stages, revealing fibrosis, angiogenesis, and metabolic alterations.

This study uses motion sequencing to analyze behavioral syllables after spinal cord injury, revealing recovery patterns shaped by injury severity and individual differences.

The paper develops BIKO, an ontology to standardize terminology and methodologies in TBI research to improve data comparison and translation from preclinical to clinical settings.

This study investigates the association between enlarged perivascular spaces (ePVS) and white matter injury, brain atrophy, cognitive decline, and inflammation markers in CADASIL, finding ePVS correlates with these pathologies and specific plasma proteins.

The paper examines associations between circulating angiogenesis markers and brain aging trajectories in humans, finding sex-specific effects and implications for vascular cognitive impairment.

This paper develops an AutoML framework with explainable AI tools to identify hemodynamic predictors of spinal cord injury outcomes.

The paper introduces ODC-TBI, a platform for sharing preclinical TBI data, enabling big data analytics and machine learning to address heterogeneity in TBI research.

The paper identifies soluble TNF receptor 1 (sTNFR1) as a therapeutic target for spinal cord injury using multi-dimensional analysis of preclinical data.

This study uses ex vivo diffusion MRI and histopathology to correlate tract disruptions with axonal injury in a TBI patient.

The paper identifies 197 genes in peripheral blood cells whose expression correlates with acute spinal cord injury severity, achieving 72.7% accuracy in predicting injury grades.

This study compares DTI and NODDI biomarkers in mTBI patients to assess white matter changes over time and their association with cognitive recovery.