Ann Marie Stowe

The paper identifies age-associated B cells (ABCs) in the CNS that develop from a localized progenitor pool and contribute to impaired post-stroke recovery in mice.

This study investigates the effects of PLCγ2 deficiency in mice, showing impaired immune tolerance, myelin homeostasis disruption, and enhanced oxidative metabolism in the brain.

This study uses long-read single-cell sequencing to analyze isoform-level diversity in human PBMCs, identifying novel isoforms and cell-type-specific patterns.

This study shows that High-Low training improves respiratory function and reduces anxiety-like behaviors in a rodent model of chronic spinal cord injury.

This study shows that B cells modulate hippocampal neuronal activity after stroke, with effects dependent on age, sex, and injury status.

The paper compares gene expression in perilesional and contralesional cortex after stroke, finding shared inflammatory responses and microglia signaling in both regions across sexes.

The paper develops a functional MRI atlas for hypertensive older adults, addressing age-related changes not captured by standard atlases.

This study examines the association between terminally differentiated effector memory T cells (TEMRAs) and cognitive and AD-related biomarkers in an aging cohort, finding CD8+ TEMRAs correlate with neuroinflammation markers.

This study shows that blood vessel regression in the brain reduces neuronal activity by impairing mitochondrial metabolism and glutamate production.

The paper exposes male mice to space radiation and finds no detrimental effect on high-level cognition, with improved pattern separation performance.