Author

O. Fedorov

InSysBio (Russia)ORCID 0000-0001-9004-1815Unclaimed ORCID profile · follow to get notified of new preprints

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O. Fedorov7 papers

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Aleksandra Andreevna Gorkovskaia· 1 shared Aleksandra VasilevaiD· 1 shared Alina Demkina· 1 shared Anna B. TrofimovaiD· 1 shared Bogdan KirilloviD· 1 shared Katherine Vilinski-Mazur· 1 shared Konstantin SeverinoviD· 1 shared Marina AbramovaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Aleksandra Andreevna Gorkovskaia

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1 paper

Recent·Most cited

Sequencing-Free Protospacer-Adjacent Motif Discovery for Uncharacterized CRISPR-Cas9 Orthologs via Active Learning

Bogdan Kirillov, Aleksandra Vasileva, O. Fedorov, Yuliya Kuz'mina, Matvey Kolesnik, Anna B. Trofimova, Alina Demkina, Viktoriia Ronchikova, Mariya Drozhzhina, Marina Abramova, Aleksandra Andreevna Gorkovskaia, Polina V Malysheva, Katherine Vilinski-Mazur, Mikhail A. Khodorkovskii, Maxim Panov, Konstantin Severinov

This paper introduces an active learning method to discover PAMs for uncharacterized CRISPR-Cas9 orthologs without sequencing, reducing data requirements and validating it on known and novel Cas9 variants.

bioRxiv · Oct 21, 2026 · PreprintBioengineering