NeuroscienceNeurobiology of DiseasePeer-reviewed
Immune receptor LAG3 regulates microglia function duringAlzheimer's disease
Andrew T. Perl, Juan Wu, John D. Dong…·Elizabeta Gjoneska
This study shows that deleting the immune receptor Lag3 in a familial AD mouse model reduces amyloidosis, microgliosis, and behavioral deficits, suggesting Lag3 as a potential therapeutic target for Alzheimer's disease.
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