Author

Elizabeta Gjoneska

Broad InstituteORCID 0000-0002-3255-4740Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:ChIP-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Ashley M. BrooksiD· 2 shared Alex J. MarchiiD· 1 shared Alexander MeissneriD· 1 shared Andreas R. PfenningiD· 1 shared Andrew R. Yoblinski· 1 shared Andrew T. PerliD· 1 shared Anna Y. Tang· 1 shared B BernsteiniD· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Ashley M. BrooksORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Alzheimer's Disease Risk Allele APOE4 Interacts with Arsenic Exposure to Drive Microglial Dysfunction

Alex J. Marchi, Ashley M. Brooks, Elizabeta Gjoneska

This study shows that the APOE4 allele increases microglial vulnerability to arsenite exposure through transcriptional and functional changes.

bioRxiv · May 12, 2026 · PreprintNeuroscience

Immune receptor LAG3 regulates microglia function duringAlzheimer's disease

Andrew T. Perl, Juan Wu, John D. Dong, Ashley M. Brooks, Andrew R. Yoblinski, Tia T. Vierling, Jian‐Liang Li, Dana R Ruby, Daniel Radzicki, Serena M. Dudek, Jesse D. Cushman, Elizabeta Gjoneska

This study shows that deleting the immune receptor Lag3 in a familial AD mouse model reduces amyloidosis, microgliosis, and behavioral deficits, suggesting Lag3 as a potential therapeutic target for Alzheimer's disease.

Neurobiology of Disease · May 12, 2026Peer-reviewedNeuroscience

Epigenome-wide study uncovers tau pathology-driven changes of chromatin organization in the aging human brain

Hans‐Ulrich Klein, Cristin Aubin, Elizabeta Gjoneska, Sarah E. Sullivan, Belinda J. Kaskow, Anna Y. Tang, Robert V. Smith, Jishu Xu, Andreas R. Pfenning, B Bernstein, Alexander Meissner, Julie A. Schneider, Sara Mostafavi, Li‐Huei Tsai, Tracy L. Young‐Pearse, , Philip L. De Jager

This study identifies tau pathology-driven chromatin organization changes in aged human brains and shows these effects can be reversed with HSP90 inhibitors.

Nature Neuroscience · Dec 12, 2018Peer-reviewedNeuroscience