Author

Hafsa M. Mire

Broad InstituteORCID 0000-0001-9293-2953Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:DNA methylation· 1 Assay:proteomics· 1

Frequent Co-Authors

Soumya RaychaudhuriiD· 2 shared Accelerating Medicines Partnership: RA/SLE Network· 1 shared Annelise Yoo Mah-SomiD· 1 shared Aparna NathaniD· 1 shared C.-J. Liu· 1 shared David R. LiuiD· 1 shared Gregory A. NewbyiD· 1 shared Jeffrey A. SparksiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersGenetics

Soumya RaychaudhuriORCID

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2 papers

Recent·Most cited

Identifying the causal allele in the CD40 autoimmune locus enables discovery of context-specific trans-effects in B cells

Yoshihiko Tomofuji, Zepeng Mu, Hafsa M. Mire, Yu Zhao, C.-J. Liu, Vidya Jayanthi, Nicholas W. Sugiarto, Accelerating Medicines Partnership: RA/SLE Network, Jeffrey A. Sparks, Soumya Raychaudhuri

The paper identifies a causal allele in the CD40 locus and demonstrates context-specific trans-effects in B cells using CITE-seq and CRAFT-seq.

bioRxiv · Aug 4, 2026 · PreprintGenetics

Defining the function of disease variants with CRISPR editing and multimodal single cell sequencing

Yuriy Baglaenko, Michelle L. Curtis, Majd Al Suqri, Ryan Agnew, Aparna Nathan, Hafsa M. Mire, Annelise Yoo Mah-Som, David R. Liu, Gregory A. Newby, Soumya Raychaudhuri

The paper uses CRISPR editing and multimodal single-cell sequencing to identify the functional effects of disease variants in primary human cells.

bioRxiv · Mar 28, 2024 · PreprintGenomics