Ameen Abdulla Salahudeen

This study uses single-cell and spatial transcriptomics to analyze early stages of squamous cell carcinoma in mice and humans, identifying transcriptomic programs linked to therapeutic resistance.

SpinAdapt is an unsupervised RNA correction algorithm that enables transfer of molecular models between labs without requiring patient-level data, improving reproducibility and privacy.

This paper identifies HAT1 as a gene that links nutrient metabolism to histone production through a gene-metabolite circuit, showing its role in cell proliferation and its association with cancer outcomes.