Author

Maeve S. McNamara

Harvard UniversityORCID 0000-0001-9043-0212Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alice E. KaneiD· 2 shared David A. SinclairiD· 2 shared Patrick T. GriffiniD· 2 shared Alexandre TrappiD· 1 shared Amber L. MuelleriD· 1 shared Colleen Carmody· 1 shared Csaba KerepesiiD· 1 shared Daniel L. VeraiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMolecular Biology

Alice E. KaneORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintDec 16, 2025

DNA methylation signatures of frailty beyond age: a longitudinal study of female and male mice

Dantong Zhu, Shyleen Frost, Patrick T. Griffin…·Alice E. Kane

This study identifies DNA methylation signatures associated with frailty in mice, distinguishing age-independent and -dependent mechanisms and revealing sex-specific patterns.

DOI 10.64898/2025.12.13.694109

mouseDNA methylation

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GenomicsbioRxivPreprintOct 25, 2021

TIME-Seq Enables Scalable and Inexpensive Epigenetic Age Predictions

Patrick T. Griffin, Alice E. Kane, Alexandre Trapp…·David A. Sinclair

The paper introduces TIME-Seq, a low-cost method for epigenetic age prediction, and validates it on mouse and human samples, showing improved scalability and accuracy.

11 citations

mousehuman

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