IFNγ-Expressing Myeloid Cells Localize within Lipoproteinosis during Drug-Associated Pulmonary Alveolar Proteinosis occurring in Systemic Juvenile Idiopathic Arthritis
Alea C. Delmastro, Candace C. Liu, Xiaowen Ding, Serena Y. Tan, Inna Averbukh, Marc MB Bosse, Timothy Keyes, Surbhi Sharma, Gail H. Deutsch, Michael Angelo, Vivian E Saper, Elizabeth Mellins, Erin McCaffrey
This study identifies IFNγ-expressing myeloid cells in lipoproteinosis regions of sJIA-daPAP patients, suggesting their role in immune pathology.
bioRxiv · Nov 22, 2024 · PreprintImmunology