Asymmetric induction of IL-23R by CpG and IL-15 in proliferative CLL fractions highlights intraclonal heterogeneity in chronic lymphocytic leukemia
Martina Cardillo, Nadia Bertola, Fabiana Ferrero…·Giovanna Cutrona
The paper shows that CpG and IL-15 induce IL-23R in CLL cells, with proliferative subfractions showing higher expression, suggesting a pathogenic mechanism.