Author

Adrianos Skaros

Human TechnopoleORCID 0000-0001-7261-3162Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:CRISPR screen· 1

Frequent Co-Authors

Giuseppe TestaiD· 3 shared Sebastiano TrattaroiD· 3 shared Alessandro VitrioloiD· 2 shared Carlo Emanuele VillaiD· 2 shared Daniele CapocefaloiD· 2 shared Erika TenderiniiD· 2 shared Flavia TroglioiD· 2 shared Marija MihailovichiD· 2 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Giuseppe TestaORCID

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3 papers

Recent·Most cited

Systems BiologybioRxivPreprintApr 28, 2025

Regulatory logic of human cortex evolution by combinatorial perturbations

Adrianos Skaros, Alessandro Vitriolo, Oliviero Leonardi…·Giuseppe Testa

The paper uses combinatorial CRISPR-Cas9 perturbations in brain organoids to uncover regulatory hierarchies of human-specific genes involved in cortical evolution.

DOI 10.1101/2025.04.28.651083

humanCRISPR screen

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NeuroscienceScience AdvancesPeer-reviewedNov 29, 2023

GTF2I dosage regulates neuronal differentiation and social behavior in 7q11.23 neurodevelopmental disorders

Alejandro Tobon, Reinald Shyti, Carlo Emanuele Villa…·Giuseppe Testa

This study shows that GTF2I dosage affects neuronal differentiation and social behavior in 7q11.23 neurodevelopmental disorders using patient-derived organoids and mouse models.

40 citationstop 3%

humanproteomics

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NeurosciencebioRxivPreprintOct 10, 2022

7q11.23 CNV alters protein synthesis and REST-mediated neuronal intrinsic excitability

Marija Mihailovich, Pierre‐Luc Germain, Reinald Shyti…·Giuseppe Testa

This study investigates how 7q11.23 CNVs affect protein synthesis and neuronal excitability in neurodevelopmental disorders using patient-derived neurons and multi-omics approaches.

6 citations

humanproteomics

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