Jumpei Nogami

This study identifies Hoxa10 as a mediator of positional memory in adult skeletal muscle stem cells, linking embryonic gene expression to region-specific regenerative capacity.

The paper tracks H3K27me3 and H4K20me1 dynamics during XCI and finds they accumulate concurrently but have distinct genomic distributions, with H4K20me1 possibly contributing to chromatin compaction.

This study identifies four temporal patterns of calcineurin-dependent gene expression during skeletal muscle differentiation and shows Cn promotes gene expression by facilitating chromatin remodeling and transcription factor interactions.