Author

Hanna Witwicka

University of Massachusetts Chan Medical School

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Anthony N. ImbalzanoiD· 3 shared Sabriya A. SyediD· 2 shared Tapan SharmaiD· 2 shared Teresita Padilla‐BenavidesiD· 2 shared Daniel C.L. RobinsoniD· 1 shared Francis Jeffrey DilworthiD· 1 shared Jumpei NogamiiD· 1 shared Kazumitsu MaeharaiD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

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10 top collaborators · 27 mutual co-author links

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3 shared papersMolecular Biology

Anthony N. ImbalzanoORCID

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3 papers

Recent·Most cited

Differential requirements for different subfamilies of the mammalian SWI/SNF chromatin remodeling enzymes in myoblast differentiation

Teresita Padilla‐Benavides, Monserrat Olea‐Flores, Tapan Sharma, Sabriya A. Syed, Hanna Witwicka, Miriam D. Zuñiga‐Eulogio, Kexin Zhang, Napoleón Navarro‐Tito, Anthony N. Imbalzano

The paper investigates the roles of three mSWI/SNF subfamilies in myoblast differentiation, finding distinct requirements for BAF and ncBAF complexes, while PBAF is dispensable.

International Journal of Molecular Sciences · Jul 9, 2023Peer-reviewedMolecular Biology

The Bromodomains of the mammalian SWI/SNF (mSWI/SNF) ATPases Brahma (BRM) and Brahma Related Gene 1 (BRG1) promote chromatin interaction and are critical for skeletal muscle differentiation

Tapan Sharma, Daniel C.L. Robinson, Hanna Witwicka, Francis Jeffrey Dilworth, Anthony N. Imbalzano

This study shows that bromodomains in BRG1 and BRM promote chromatin binding and are essential for skeletal muscle differentiation by regulating gene expression and cell cycle exit.

Nucleic Acids Research · Jul 8, 2021Peer-reviewedMolecular Biology

Calcineurin broadly regulates the initiation of skeletal muscle-specific gene expression by binding target promoters and facilitating the interaction of the SWI/SNF chromatin remodeling enzyme

Hanna Witwicka, Jumpei Nogami, Sabriya A. Syed, Kazumitsu Maehara, Teresita Padilla‐Benavides, Yasuyuki Ohkawa, Anthony N. Imbalzano

This study identifies four temporal patterns of calcineurin-dependent gene expression during skeletal muscle differentiation and shows Cn promotes gene expression by facilitating chromatin remodeling and transcription factor interactions.

Molecular and Cellular Biology · Jul 11, 2019Peer-reviewedMolecular Biology