Distinguishing Pseudotransduction and True Transduction Enables Characterization and Bioengineering of Extracellular Vesicle-Adeno-Associated Virus Vectors
Jonathan D. Boucher, Devin M. Stranford, Hailey I. Edelstein, Danielle Tullman‐Ercek, Neha P. Kamat, Joshua N. Leonard
The paper develops an assay to distinguish pseudotransduction from true transduction in EV-AAV vectors, revealing cell-type-specific effects of EV modifications on transduction efficiency.
Journal of Extracellular Vesicles · Apr 1, 2026Peer-reviewedBioengineering