Neha P. Kamat

CELLISA is a cell-cell binding assay that accelerates discovery of EV targeting constructs by predicting cell-EV interactions through high-throughput screening of cell surface-displayed proteins.

The paper develops an assay to distinguish pseudotransduction from true transduction in EV-AAV vectors, revealing cell-type-specific effects of EV modifications on transduction efficiency.

This paper develops a DNA-tethering method to rapidly assemble bispecific lipid nanoparticles for targeted T cell mRNA delivery, showing improved targeting and transfection compared to single-targeted LNPs.

This paper develops a cell-free method to produce Nipah virus membrane proteins in liposomes for vaccine design, showing improved protein incorporation and enhanced immune responses in mice.

This study introduces a lipid-foam tissue mimetic that exhibits self-healing and reorganization through tension fluctuations induced by active particles.

The paper introduces a synthetic method to assay polycystin ion channel biophysics and characterizes their functional properties.

This study investigates how hydrophobic mismatch affects membrane protein organization using protein design, simulations, and cell-free systems, showing deformation of membranes and controlled protein assembly.

This study demonstrates how bacterial two-component systems can be used to enable transmembrane signaling in synthetic membranes, showing that performance can be tuned by altering membrane properties and protein engineering.

This paper improves cell-free expression of membrane proteins by identifying factors affecting synthesis and developing a model to optimize yield through membrane composition and N-terminal domain sequence adjustments.

This paper demonstrates a cell-free biosensor encapsulated in lipid vesicles that detects fluoride with tunable sensitivity and real-world applicability.

This study demonstrates that bacterial microcompartments chemotax towards their substrate and are protected from aggregation in a cell-free system.

The paper improves cell-free glycoprotein synthesis by characterizing and enriching native membrane vesicles in bacterial extracts to enhance membrane-bound functionality.

This paper demonstrates DNA-functionalized vesicles that enable targeted fusion and controlled protein expression in vitro.