Author

Yoshikazu Hirate

Tokyo Medical and Dental UniversityORCID 0000-0001-9116-3603Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yoshikazu Hirate1 paper

Biology Disciplines

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Molecular Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Masami Kanai‐AzumaiD· 3 shared Tsutomu EndoiD· 3 shared Yoshifumi Fujioka· 3 shared Fumitoshi IshinoiD· 2 shared Hikaru ItoiD· 2 shared Hiroshi KiyonariiD· 2 shared Hirosuke ShiuraiD· 2 shared Masayuki Ishii· 2 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Masami Kanai‐AzumaORCID

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3 papers

Recent·Most cited

Developmental BiologyReproductionPeer-reviewedOct 19, 2026

Selective depletion of AMH-expressing granulosa cells in vivo impairs follicular development and fertility in female mice

Tsutomu Endo, Mayu Tamemasa, Kana Hayakawa…·Masami Kanai‐Azuma

DOI 10.1093/reprod/xaag131

mouseexperimental assay

Molecular BiologybioRxivPreprintAug 2, 2024

Targeting of retrovirus-derived Rtl8a/8b reduces social response and increases apathy-like behavior associated with GABRB2 reduction

Yoshifumi Fujioka, Hirosuke Shiura, Masayuki Ishii…·Fumitoshi Ishino

This study shows that knocking out Rtl8a and Rtl8b in mice leads to reduced social behavior, increased apathy, and obesity, likely due to decreased GABRB2 expression in the brain.

4 citations

mousebulk RNA-seq

Molecular BiologybioRxivPreprintMay 28, 2023

Targeting retrovirus-derived Rtl8a and 8b causes late onset obesity and neurodevelopmental defects

Yoshifumi Fujioka, Hirosuke Shiura, Masayuki Ishii…·Fumitoshi Ishino

This study shows that Rtl8a and Rtl8b double knockout mice develop late-onset obesity and neurodevelopmental defects, indicating these retrovirus-derived genes are important for brain function.

2 citations

mouseexperimental assay