Jennifer M. Mason

This study shows RAD54L promotes nascent DNA degradation and radial chromosome formation in FANC-deficient cells, aiding in interstrand crosslink repair.

This study shows NEK8 overexpression inhibits homologous recombination and sensitizes cells to PARP inhibitors, suggesting potential therapeutic targeting in NEK8-overexpressing cancers.

The paper shows FBH1 limits PRIMPOL-mediated DNA synthesis at stalled replication forks but PRIMPOL does not prevent double strand break formation in FBH1 knockout cells.

This study shows RAD51's non-enzymatic roles in replication fork processing and restart, revealing its function in fork reversal and promoting replication restart through both enzymatic and non-enzymatic mechanisms.