Joshua D. Clugston

This study investigates shear strain stiffening in cartilage, showing it results from a mechanical phase transition between bending- and stretching-dominated modes, influenced by collagen concentration and compression.

This study shows that FMNL2 regulates melanoma cell morphology and motility in response to substrate stiffness, with its depletion enhancing stress fiber alignment and impairing motility on stiff substrates.