Author

Isabel C. Lewis

Kansas State UniversityORCID 0000-0001-9142-7277Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:perturbation response prediction· 1 Organism:yeast· 1

Frequent Co-Authors

Erianna M. BasgalliD· 1 shared Gregory C. FinniganiD· 1 shared Megan E. GoeckeliD· 1 shared Megan HalloraniD· 1 shared Samantha C. GoettingiD· 1 shared Yao Yan· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperSynthetic Biology

Erianna M. BasgallORCID

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1 paper

Recent·Most cited

Modulating CRISPR gene drive activity through nucleocytoplasmic localization of Cas9 in S. cerevisiae

Megan E. Goeckel, Erianna M. Basgall, Isabel C. Lewis, Samantha C. Goetting, Yao Yan, Megan Halloran, Gregory C. Finnigan

This study uses an artificial gene drive system in budding yeast to show that appending nuclear localization signals to Cas9 can modulate nuclease activity and act as a molecular safeguard.

Fungal Biology and Biotechnology · Feb 4, 2019Peer-reviewedSynthetic Biology