Samantha J. Riesenfeld

This study shows how V{gamma}4 IELs use both germline and non-germline TCR features to sustain persistent BTNL3/8 recognition and express an NK-like program in the gut.

This study shows that loss of Tet2 allows T cells to produce IL-4 autonomously, leading to chronic Th2 responses and allergic pathology.

The paper introduces TopicVelo, a method to improve RNA velocity estimation by integrating bursty transcriptional dynamics, enabling accurate process-specific velocity inference and transition analysis.

This study constructs a single-cell and spatial atlas of the choroid plexus in developing and adult mice, revealing cell types, regional gene expression, and cell-cell interactions.

The paper introduces a statistical method to distinguish real cells from empty droplets in single-cell RNA sequencing data, improving detection of low-UMI cell libraries while controlling false discovery rates.