Author

Cary O. Harding

Oregon Health & Science UniversityORCID 0000-0001-9146-3112Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Anne VonadaiD· 2 shared Michael MartineziD· 2 shared Adrian M. BarisiD· 1 shared Amita TiyaboonchaiiD· 1 shared Daelyn Y. RichardsiD· 1 shared Laura Harper· 1 shared Leslie WakefieldiD· 1 shared Markus GrompeiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersGenomics

Anne VonadaORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintFeb 24, 2025

Enhancement of Therapeutic Transgene Insertion for Murine Phenylketonuria

Michael Martinez, Daelyn Y. Richards, Shelley R. Winn…·Cary O. Harding

This study improves HDR-mediated gene insertion in mice with PAH deficiency by inhibiting competing DNA repair pathways, achieving transgene integration in 10% of alleles and reducing serum phenylalanine by 70.6%.

1 citation

mouseexperimental assay

𝕏 PostBluesky

GeneticsHepatologyPeer-reviewedOct 12, 2023

Complete correction of murine phenylketonuria by selection-enhanced hepatocyte transplantation

Anne Vonada, Leslie Wakefield, Michael Martinez…·Amita Tiyaboonchai

This paper corrects a mouse model of phenylketonuria by transplanting Cypor-deficient hepatocytes selected with acetaminophen, achieving stable normalization of blood phenylalanine levels.

19 citations

mouseexperimental assay

𝕏 PostBluesky