Molecular BiologybioRxivPreprint
Deficiency of m6A RNA methylation promotes ZBP1-mediated cell death
Shuang Li, Xiangyu Deng, Deepak Pathak…·Yi‐Lan Weng
The paper shows that m6A deficiency leads to 7SK RNA activation of the RIG-I/MAVS axis and ZBP1-mediated necroptotic cell death through IFN and rG4 synergies.
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