Author

Lina Sun

Houston Methodist

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Rashmi Basavaraj· 3 shared Yi‐Lan WengiD· 3 shared Deepak Pathak· 2 shared Xiangyu DengiD· 2 shared Chao ChengiD· 1 shared Gavin Wayne BritziD· 1 shared Jianrong LiiD· 1 shared Jin WangiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersNeuroscience

Rashmi Basavaraj

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Loss of m6A unmasks a senescence-associated inflammatory program in human microglia

Deepak Pathak, Rashmi Basavaraj, Lina Sun, Yi‐Lan Weng

This study shows that reducing m6A in human microglia induces a senescence-like inflammatory state through specific RNA changes and nuclear remodeling.

bioRxiv · Jul 8, 2026 · PreprintNeuroscience

Biochemical Profiling and Structural Basis of ADAR1-Mediated RNA Editing

Xiangyu Deng, Lina Sun, Min Zhang, Rashmi Basavaraj, Jin Wang, Yi‐Lan Weng, Yang Gao

This study characterizes ADAR1's RNA editing mechanism through biochemical profiling and structural analysis, revealing sequence and duplex length dependence, disease mutation impacts, and the role of RNA-binding domain 3.

Molecular Cell · Jan 2, 2025Peer-reviewedBiochemistry

Deficiency of m6A RNA methylation promotes ZBP1-mediated cell death

Shuang Li, Xiangyu Deng, Deepak Pathak, Rashmi Basavaraj, Lina Sun, Yating Cheng, Jianrong Li, Marissa Burke, Gavin Wayne Britz, Chao Cheng, Yang Gao, Yi‐Lan Weng

The paper shows that m6A deficiency leads to 7SK RNA activation of the RIG-I/MAVS axis and ZBP1-mediated necroptotic cell death through IFN and rG4 synergies.

bioRxiv · Jun 29, 2024 · PreprintMolecular Biology